How accurate is urine cytology for bladder cancer?

How accurate is urine cytology for bladder cancer?

Urine cytology is associated with a significant false-negative rate, especially for low-grade carcinoma (10-50% accuracy rate). The false-positive rate is 1-12%, although cytology has a 95% accuracy rate for diagnosing high-grade carcinoma and CIS. Urine cytology is often the test used for diagnosis of CIS.

What does a urine cytology test show?

Urine cytology is a test to look for abnormal cells in your urine. It's used with other tests and procedures to diagnose urinary tract cancers, most often bladder cancer. Your doctor might recommend a urine cytology test if you have blood in your urine (hematuria).

Can urine cytology wrong?

The moderate sensitivity of cytology is complemented by its high specificity (range of most studies: 95% to 100%). False-positive results, in other words, are uncommon. Some investigators report finding no false-positive results in their studies34,42; others describe rates ranging from 1.

What does abnormal urine cytology mean?

Cells that appear abnormal in your urine may also indicate inflammation in the urinary tract or cancer of the bladder, kidney, ureter, or urethra. However, an abnormal urine cytology result can't diagnose these diseases. Additional tests are usually necessary to confirm the diagnosis.

Can you have bladder cancer with no blood in urine?

Among women with hematuria the rate of cancer was 1.

What are the signs of bladder cancer in a woman?

Bladder Cancer: Symptoms and Signs

• Blood or blood clots in the urine.
• Pain or burning sensation during urination.
• Frequent urination.
• Feeling the need to urinate many times throughout the night.
• Feeling the need to urinate, but not being able to pass urine.
• Lower back pain on 1 side of the body.

What is a cytology test done for?

Diagnosing diseases by looking at single cells and small clusters of cells is called cytology or cytopathology. It's an important part of diagnosing some types of cancer.

How long does it take for a cytology test to come back?

Routine biopsy and cytology results may be ready as soon as 1or 2 days after the sample gets to the lab. But there are many reasons some take much longer to complete.

How long does cytology results take?

Routine biopsy and cytology results may be ready as soon as 1or 2 days after the sample gets to the lab. But there are many reasons some take much longer to complete.

What does negative cytology mean?

Negative results mean that no abnormal cells were found. A positive result means that abnormal cells were found and that you may have a problem in your urinary tract.

What is the accuracy of urine cytology for bladder cancer?

Many studies have evaluated the accuracy of urine cytology in the detection of bladder cancer. Overall, the reported sensitivity ranges from 20% to 97.

What do you need to know about urine cytology?

Cytology is the examination of cells from the body under a microscope. In a urine cytology exam, a doctor looks at cells collected from a urine specimen to see how they look and function. ... The test commonly checks for infection, inflammatory disease of the urinary tract, cancer, or precancerous conditions.

Can a cytology test be used to diagnose cancer?

A positive result indicates that cancer cells were found in your urine. A urine cytology test can't be used alone to diagnose cancer. If atypical or cancerous cells are detected, your doctor will likely recommend a cystoscopy procedure and a CT scan to further examine your bladder and urinary tract. By Mayo Clinic Staff

Which is the best Test to detect urinary tract cancer?

Urine cytology can best detect larger and more-aggressive urinary tract cancers. It might not detect small urinary tract cancers that grow more slowly. Risks of urine cytology testing depend on how your urine is collected.